Publications

Exploring experiences of the regulatory toxicology system: system‑level promoters and inhibitors of new approach methodologies

Bearth A, Kopainsky B, Jones LB, Vist, G., Husøy, T, Svendsen C, Whaley P, Hoffmann S,· Ames HM, Solstad G, Bloch D, Čavoški A, Chiu WA, Davenport D, Davies HG, Giusti A, Hartung T, Kwon S, Osborne OJ, Rooney AA, Rousselle C, Sass JB, Wright FA, Mathisen GH

Archives of Toxicology,  18 Aug 2025


Editorial by Prof. Ellen Fritsche on PARCOPEDIA: "PARC plays a pivotal role in shaping the future of chemical risk assessment in Europe"

Ellen Fritsche

PARCOPEDIA,  25 Jul 2025


The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers

Coustillet T, Bearth, A, Coumoul X, Villégier, A-S, Bisson M, Fritsche, E, Brignon, J-M, Zeman F, Audouze, K

Toxicology,  22 Jun 2025


Zebrafish as a model to assess the neurotoxic potential of propylene glycol ethers

Puligilla RD, Roos NJ, Bolten SJ, Hopf NB, Zurich M-G, Barulin N, Huwyler J

Environmental toxicology and pharmacology,  1 Jun 2025


A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays [online ahead of print]

Carstens KE, Dönmez A, Hsieh J-H, Bartmann K, Friedman KP, Koch K, Scholze M, Fritsche E

Computational Toxicology,  30 May 2025


Multi-behavioral phenotyping in early-life-stage zebrafish for identifying disruptors of non-associative learning [online ahead of print]

Leuthold D, Herold NK, Nerlich J, Bartmann K, Scharkin I, Hallermann SJ, Schweiger N, Fritsche E, Tal T

Environmental Health Perspectives,  30 May 2025


Panel discussions on the global regulatory acceptance and harmonisation of non-animal NAMs

Courtot L, Fritsche E, Hobi N, Kleinstreuer N, Lee R, Parvatam S, Ritskes-Hoitinga M, Roper C, Westmoreland C, Gougeon E

NAM Journal,  24 May 2025


2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives [online ahead of print]

Hogberg HT, Fritsche E, Gröters S, Kovi RC, Rao DB, Terron A, Winter MJ

Toxicologic Pathology,  15 May 2025


Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs [online ahead of print]

Blum J, Bartmann K, de Paula Souza J, Fritsche E

Current Opinion in Toxicology,  2 May 2025


Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds [online ahead of print]

Carstens KE, Gronskaya E, Jäckel D, Bertoli J, Ramirez Cuevas K, Dorier J, Wang S, Lopez-Rodriguez D, Shafer TJ, Zurich M-G, Pamies D

Archives of Toxicology,  28 Apr 2025