Publications
Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes
Rudin D, Roos NJ, Duthaler U, Krähenbühl S
Toxicology, 1 Oct 2019
Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04
Brecht K, Kirchhofer C, Bouitbir J, Trapani F, Keiser J, Krähenbühl S
International Journal of Molecular Sciences, 1 Oct 2019
Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts
Bouitbir J, Alshaikhali A, Panajatovic MV, Abegg VF, Paech F, Krähenbühl S
Toxicology, 1 Oct 2019
In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice
Sandström J, Kratschmar DV, Broyer A, Poirot O, Marbet P, Chantong B, Zufferey F, Dos Santos T, Boccard J, Chrast R, Odermatt A, Monnet-Tschudi F
Archives of Toxicology, 30 Sep 2019
Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity
Calderazzo S, Tavel D, Zurich MG, Kopp-Schneider A
Archives of Toxicology, 30 Sep 2019
11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma
Beck KR, Inderbinen SG, Kanagaratnam S, Kratschmar DV, Jetten AM, Yamaguchi H, Odermatt A
Journal of Lipid Research, 30 Sep 2019
Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase
Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D
The Journal of Steroid Biochemistry and Molecular Biology, 30 Sep 2019
Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects
Feutz AC, De Geyter C
Archives of Toxicology, 31 Aoû 2019
Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle
Sanvee GM, Panajatovic MV, Bouitbir J, Krähenbühl S
Biochemical Pharmacology, 30 Jui 2019
Genetic resistance to DEHP-induced transgenerational endocrine disruption
Stenz L, Rahban R, Prados J, Nef S, Paoloni-Giacobino A
PLoS One, 10 Jui 2019