Publications

Panel discussions on the global regulatory acceptance and harmonisation of non-animal NAMs

Courtot L, Fritsche E, Hobi N, Kleinstreuer N, Lee R, Parvatam S, Ritskes-Hoitinga M, Roper C, Westmoreland C, Gougeon E

NAM Journal,  24 Mai 2025


2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives [online ahead of print]

Hogberg HT, Fritsche E, Gröters S, Kovi RC, Rao DB, Terron A, Winter MJ

Toxicologic Pathology,  15 Mai 2025


Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs [online ahead of print]

Blum J, Bartmann K, de Paula Souza J, Fritsche E

Current Opinion in Toxicology,  2 Mai 2025


Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds [online ahead of print]

Carstens KE, Gronskaya E, Jäckel D, Bertoli J, Ramirez Cuevas K, Dorier J, Wang S, Lopez-Rodriguez D, Shafer TJ, Zurich M-G, Pamies D

Archives of Toxicology,  28 Avr 2025


Dual targeted lipid nanoparticles for enhanced DNA delivery and transfection of breast cancer cells

Lotter C, Stierli MA, Deepthi Puligilla R, Huwyler J

European Journal of Pharmaceutics and Biopharmaceutics,  1 Avr 2025


Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment [online ahead of print]

Koch K, Schlüppmann K, Hüsken S, Stark LM, Förster, Masjosthusmann S, Klose J, Dönmez A, Fritsche E

Environmental International,  20 Mar 2025


Hepatic and Extra-Hepatic Metabolism of Propylene Glycol Ethers in the Context of Central Nervous System Toxicity [online ahead of print]

Werner S, Pamies D, Zurich MG, Suter-Dick L

Toxicology,  8 Fév 2025


New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use

Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF

Environment International,  1 Fév 2025


Editorial: Five grand challenges in toxicology

Fadeel B, Alexander J, Antunes SC, Dalhoff K, Fritsche E, Hogberg HT, Huaux F, Oredsson S, Pietroiusti A, Svingen T, Wilks MF

Frontiers in Toxicology,  21 Jan 2025


The long way from raw data to NAM-based information: Overview on data layers and processing steps

Blum J, Brüll M, Hengstler JG, Dietrich DR, Gruber AJ, Dipalo M, Kraushaar U, Mangas I, Terron A, Fritsche E, Marx-Stoelting P, Hardy B, Schepky A, Escher S, Hartung T, Landsiedel R, Odermatt A, Sachana M, Koch K, Dönmez A, Masjosthusmann S, Bothe K, Schildknecht S, Beilmann M, Beltman JB, Fitzpatrick S, Mangerich A, Rehm M, Tangianu S, Zickgraf FM, Kamp H, Burger G, van de Water B, Kleinstreuer N, White A, Leist M

ALTEX,  14 Jan 2025