Hormonal changes in professional printers exposed to phthalates suggesting potential disturbances of the hypothalamic–pituitary–gonadal axis

Tiberiu M. Nita , Sonja A. Wrobel , David Vernez , Holger M. Koch , Pascal Wild , Fanny Zufferey, Serge Rudaz , Ludwig Stenz , Alex Odermatt , Nancy B. Hopf

Environmental Research,  15 Feb 2026

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11 Feb 2026

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Bisphenol TMC exhibits greater estrogenic activity than Bisphenol A and three other structural analogues exemplified by higher estrogen receptor α-mediated gene expression and breast cancer cell proliferation

Joos, F. L., van Diest, R. E., Smieško, M., Jäger, M.-C., Kley, M., Odermatt, A., Bouitbir, J.

Elsevier ScienceDirect,  11 Feb 2026

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New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Ardenkjær-Skinnerup, J., Baert, Y., Bajard, L., Blum, J., Brion, F., Coppola, L., Fini, J.-B., Fritsche, E., Holbech, H., Hurem, S., Jacobs, M. N., Johansson, H. K. L., Knapen, D., Lyche, J. L., Mai, P. N. T., Neuhaus, W., Nikolov, N. G. N., Nurani, A., Papageorgiou, K., Poulsen, R., Ramhøj, L., Řehůřková, E., Rosenmai, A. K., Rüegg, J., Sovadinová, I., Tait, S., Van de Pette, M., Vanhaecke, T., Vergauwen, L., Wedebye, E. B., Xu, E. G., Svingen, T.

Frontiers,  11 Feb 2026

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Advancing the implementation of artificial intelligence in regulatory frameworks for chemical safety assessment by defining robust readiness criteria

Souza, J. de P., Blum, J., Maran, U., Sild, S., Dawson, L., Čavoški, A., Holden, L., Lee, R., Karnel, V., Meusburger, L., Fraize-Frontier, S., Walsh, A., Rivière, G., Raitano, G., Roncaglioni, A., Di Consiglio, E., Tcheremenskaia, O., Bossa, C., Wendt-Rasch, L., Puzyn, T., Fritsche, E.

Frontiers,  11 Feb 2026

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Urinary concentrations of di-butyl phthalate isomers and reproductive hormonal parameters in adult men: A systematic review with dose-response meta-analysis

Tiberiu M. Nita, David Vernez, Pascal Wild, Nelly Pitteloud, Nancy B. Hopf

Environmental Toxicology and Pharmacology,  1 Jan 2026

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Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination

Arianna Capucetti, Juliana Falivene, Chiara Pizzichetti, Irene Latino, Luca Mazzucchelli, Vivien Schacht, Urs Hauri , Andrea Raimond, Tommaso Virgilio , Alain Pulfer, Simone Mosole, Llorenç Grau- Roma, Wolfgang Bäumlr, Martin Palus, Louis Renner, Daniel Ruzek, Gabrielle Goldman Levy , Milena Foerster, Kamil Chahine, and Santiago F. Gonzalez

PNAS,  25 Nov 2025

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Neurotoxicity of propylene glycol butyl ether: Multiomic evidence from human brainspheres

David Lopez-Rodriguez, David Pamies, Julien Boccard, Isabel Meister, Mathieu Galmiche, Tatjana Sajic, Estelle Maret, Noéline Héritier, Massimo Frangiamone, Aurélien Thomas, Nancy B. Hopf, Serge Rudaz, Marie-Gabrielle Zurich

Environment International,  22 Okt 2025

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Exploring experiences of the regulatory toxicology system: system‑level promoters and inhibitors of new approach methodologies

Bearth A, Kopainsky B, Jones LB, Vist, G., Husøy, T, Svendsen C, Whaley P, Hoffmann S,· Ames HM, Solstad G, Bloch D, Čavoški A, Chiu WA, Davenport D, Davies HG, Giusti A, Hartung T, Kwon S, Osborne OJ, Rooney AA, Rousselle C, Sass JB, Wright FA, Mathisen GH

Archives of Toxicology,  18 Aug 2025

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Editorial by Prof. Ellen Fritsche on PARCOPEDIA: "PARC plays a pivotal role in shaping the future of chemical risk assessment in Europe"

Ellen Fritsche

PARCOPEDIA,  25 Jul 2025