Publications

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

Terron A, Bal-Price A, Paini A, Monnet-Tschudi F, Bennekou SH, EFSA WG EPI1 Members, Leist M, Schildknecht S

Archives of Toxicology,  31 Jan 2018


Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software

Marsousi N, Desmeules JA, Rudaz S, Daali Y

Biopharmaceutics & Drug Disposition,  31 Jan 2018


Navigating in vitro bioactivity data: investigating available resources using model compounds

Ilmjarv S, Augsburger F, Tjalling Bolleman J, Liechti R, Bridge A, Sandström J, Jaquet V, Xenarios I, Krause KH

bioRxiv,  17 Jan 2018


Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

Mamoulakis C, Tsarouhas K, Fragkiadoulaki I, Heretis I, Wilks MF, Spandidos DA, Tsitsimpikou C, Tsatsakis A

Pharmacology & Therapeutics,  31 Dec 2017


Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Randazzo GM, Tonoli D, Strajhar P, Xenarios I, Odermatt A, Boccard J, Rudaz S

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences,  15 Dec 2017


ART, Stoffenmanager, and TRA: A Systematic Comparison of Exposure Estimates Using the TREXMO Translation System

Savic N, Gasic B, Vernez D

Annals of Work Exposures and Health,  15 Dec 2017


Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

González-Ruiz V, Pezzatti J, Roux A, Stoppini L, Boccard J, Rudaz S

Journal of Chromatography. A.,  8 Dec 2017


Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M

Archives of Toxicology,  30 Nov 2017


PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

Kiene K, Schenk SH, Porta F, Ernst A, Witzigmann D, Grossen P, Huwyler J

European Journal of Pharmaceutics and Biopharmaceutics,  31 Oct 2017


Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data

Savic N, Gasic B, Schinkel J, Vernez D

Annals of Work Exposures and Health,  1 Oct 2017