Training objectives 

• Explain the REACH regulatory framework
• Become familiar with modelling tools
• Provide an approach on how to select an appropriate tool for a given set of exposure conditions
• Better interpret results generated by exposure assessment models

Language: English / Registration deadline: 8 March 2021

First presentation of HESI Environmental Epidemiology Committee Webinar Series held by Prof. Harvey Checkoway (University of California, San Diego). Thu, Mar 18, 2021 6:00 PM - 7:00 PM CET.

Webinar Abstract: Well-formulated epidemiologic investigations of adverse health risks associated with environmental exposures can contribute substantially to knowledge about disease etiology and risk assessment that can lead to disease prevention. Research can span a range of study approaches, from case series reports of unexpected rare disease occurrence to longitudinal cohort studies of relatively common adverse outcomes. Illustrative examples are case reports of soft tissue sarcoma among residents exposed to dioxin from a trichlorophenol plant explosion to cross-sectional and longitudinal epidemiologic studies of parkinsonism associated with occupational manganese exposure.

Two sessions, 11 and 18 March 2021, 16:00-17:30 CET

Toxicology is an extensive and increasingly interdisciplinary field that includes the study of the adverse effects of chemicals, drugs, and natural products on humans, animals, and the environment. There is a wide variety of resources such as programs, websites, projects, software, tools, databases, and knowledge sources that have been developed to facilitate research in toxicology. The OpenTox Spring Webinars will be focussed on presenting, explaining, and discussing these resources including their applications and limitations.

With live, semi-live, and on-demand offerings, attendees will have access to 70+ Scientific and Featured Sessions, dedicated networking spaces to connect with friends and colleagues, and service and product providers through the ToxExpo exhibits.

The SOT Virtual Meeting will capture all the opportunities, activities, and scientific presentations that are hallmarks of the Society’s annual event. This includes creating areas where attendees can relax and connect, incorporating live chats into Scientific Sessions, providing on-demand presentations, and more ...

Two sessions, 11 and 18 March 2021, 16:00-17:30 CET

Toxicology is an extensive and increasingly interdisciplinary field that includes the study of the adverse effects of chemicals, drugs, and natural products on humans, animals, and the environment. There is a wide variety of resources such as programs, websites, projects, software, tools, databases, and knowledge sources that have been developed to facilitate research in toxicology. The OpenTox Spring Webinars will be focussed on presenting, explaining, and discussing these resources including their applications and limitations.

Tuesday, 9 March 2021 - 16:00 CET

This webinar panel session will discuss a number of topics with regards to emerging methods and best practices for in vitro systems which are increasingly used for biological research, toxicology, design and screening, disease modelling, and diagnostics. In particular, the focus will be on practices required for ensuring quality and reproducibility of results including good cell culture practice, documentation, and transfer of protocols, data management and analysis, comparison of methods, and reporting of information.

Objectives of the meeting:

• Critical assessment of general and specific learnings of the EU-ToxRisk project and its resulting key deliverable, the Advisory document on NAM-enhanced read-across, including feedback and endorsements from the Regulatory Advisory Board, the OECD IATA Case Studies Project, and international regulatory toxicologists, as well as outlining of remaining challenges (Session 1).
• Presentation of novel running case studies with new challenging regulatory and scientific questions, such as testing of chemicals with little or no observed adverse effects, with multi-target organ toxicity, which undergo metabolism, or with the need for ab-initio risk assessment (Sessions 2+3).
• Outlook towards future validation approaches and application of NAMs for risk assessment in new frameworks, projects, and partnerships, including a platform to jump-start new efforts in next-generation risk assessment (Sessions 4+5).

23 February 2021, 11am EST

Presenter: Andy Nong, PhD

In this presentation, we will see different research scenarios where toxicokinetic modeling was involved converting dose exposure for purposes of priority setting and screening-level risk assessment of chemicals classes.  The examples will range from rare earth metals, in-commerce list, and domestic substance list and polyfluoroalkyl substances.  We will find out how the development of predictive tools and informed utility of non-traditional toxicity data is being viewed in a regulatory decision-making context.

EUFEPS started to establish the series “EUFEPS Talks”, to strengthen the scientific exchange in pharmaceutical sciences at the European level.

Next talk on Februar 22, 2021 from 4 pm – 5 pm CET, held by Sjaak Bot (Senior Advisor Global Regulatory Affairs Janssen)

The devasting Covid-19 crisis asks for efficient and timely regulatory readiness and response to catalyze access to effective and safe vaccines and medicines. Finding here the right balance is a challenge for all stakeholders, i.e. industry, authorities and society at large. We see now the first Covid-19 vaccines being approved and deployed, more are expected to come. An accomplishment in terms of speed and efficiency never seen before. But also with inherent scientific and public debate. In this EUFEPS Talk we will discuss this regulatory balancing act where there is never a dull moment.

Registration is free of charge and we offer attractive lectures and a virtual poster session. The meeting will be held in English.