Beyond two main topics, presentations on actual and relevant topics from the different disciplines of toxicology and safety sciences will be provided.

The theme for the 23rd SETAC Europe LCA Case Study Symposium is Life Cycle Assessment for Decision Support. The focus of these two days is on case studies that highlight both solutions and challenges when applying consequential modelling for comparisons of products, projects, and strategies. The various sessions of the scientific programme cover all aspects of the application of LCA to decision making in business practice, environmental product declarations, due diligence, social responsibility, environmental management, and policy development.

The topics of the conference are: defined approaches towards regulatory acceptance, simulations of exposure and transport, integration and interoperability: software, integration and interoperability: data, high-content imaging and characterization of experimental conditions. Including session "Defined Approaches Towards Regulatory Acceptance" chaired by Prof. Martin Wilks, SCAHT, and "High-Content Imaging" chaired by Prof. Bob van der Water, Leiden, coordinator of EUToxRisk. Further information.

The event starts on the evening of 15 November 2017 with a poster presentation and networking session. On 16 November, a plenary session will be dedicated to LRI projects impact with focus on environmental and human health questions, including non-extractable residues, ecosystems services, chemical activity, biodegradation, bioaccumulation, carcinogenicity and inhalation nanotoxicology. This will be followed by a thematic session on: “Making sense of Omics for regulatory applications”. 

Leading scientists from across the world will take part in the colloquium to explore future directions for evidence integration in human risk assessment of chemicals.

In Part-2, more emphasis will be put on skin sensitization models such as h-clat (OECD TG 442E), DPRA (OECD TG 442C) or LuSens. The participants will also perform the IL/18 epiderm for identification and classification of skin sensitizing chemicals (MatTek) as well as the GARD skin sensitization test that detects potency (Senzagen).

In light of the limitations of existing non-animal based hazard assessment methodologies, particularly in the area of repeated dose as well as developmental and reproductive toxicity, readacross is currently considered to be the most applicable strategy in support of chemical’s hazard assessment. In this context, in silico tools play a critical role in identifying and justifying analogues suitable for the assessment of chemicals for which hazard data are lacking. This training co-organised with Toxminds is designed to give the necessary background along with tailored case studies to provide hands-on experience how in silico tools can be used in supporting a chemical’s hazard assessments: for example as stand-alone tools or for the identification and justification of analogues for use in read-across.  

The 2017 Scientific Program features a diverse range of scientific sessions organized into two themed tracks and covering issues such as Addressing Safety in Oncology, Translational Safety Pharmacology, Suicidality, New Modalities and New Biological Entities, Disease Models/Personalized Medicine, Microphysiological Systems - New Technologies, In Silico Modeling, Right Species-Right Time, Changing Regulatory Environment and more.

The goal of this workshop is to make attending scientists familiar with the design and conduct o typical in vitro experiments that are performed to profile the hepatic disposition characteristics of new drug candidates and/or xenobiotics. Focus will be on sound protocols for generating high quality in vitro data that can subsequently be used as input in physiologically-based pharmacokinetic (PBPK) models.

The 13th [BC]2 - the Basel Computational Biology Conference - is the key computational biology event in Switzerland in 2017 uniting scientists working in a broad range of disciplines, including bioinformatics, computational biology, neuroscience, medicine, and systems biology. Participation at [BC]2 will be the opportunity to learn about cutting-edge research in computational biology and bioinformatics.